For some reason I've had Medusa on the mind, and have been toying with artwork of her. Depending on which account you read, she was either born that way as one of the three Gorgons, or she was turned that way by a jealous Athena (which makes one wonder, why were the Greek gods so insecure? Always turning humans into something else on a whim and then there's Zeus, horndogging it after almost anything in a short toga).
So I had it in my mind, what would her reaction be when the change happened? Quite a bit of shock, I'd say. This is only a rough idea of that. Let's see where this goes.